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 John A. Curci, M.D., F.A.C.S.Vascular Surgery
Assistant Professor, Surgery
Division of General Surgery
Vascular Surgery Section
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Vascular Surgery--Certified
General Surgery--Certified
Dr. Curci specializes in vascular surgery, endovascular surgery and heart disease. His areas of clinical interest include carotid and brachiocephalic artery diseases; aneurysmal, occlusive and embolic disease of the thoracic and abdominal aorta; mesenteric and renal vascular diseases; peripheral arterial diseases; surgery for hemodialysis and chronic venous access; venous insufficiency or ulceration; and abdominal aortic aneurysm (AAA).
Yale University School of Medicine, New Haven, Conneticut, 1994
Residency: Surgery, Barnes-Jewish Hospital at Washington University School of Medicine, St. Louis, Missouri, 1999
Research Fellowship: Vascular, Washington University School of Medicine, St. Louis, Missouri, 1998
Clinical Fellowship: Vascular, Barnes-Jewish Hospital at Washington University School of Medicine, St. Louis, Missouri, 2003
Center for Advanced Medicine
Heart and Vascular Center
4921 Parkview Place, Suite A, Floor 8
St. Louis, MO 63110
(314) 362-7406
Fax: (314) 747-3548
Barnes-Jewish West County Hospital
Professional Building 1
1040 N. Mason Rd
Suite 120
Creve Coeur, MO
(314) 362-7406
(314) 362-7406
Barnes-Jewish Hospital
St. Louis Children's Hospital
John Cochran Veterans Administration Hospital
National Heart, Lung and Blood Institute, NIH
American Heart Association
The Flight Attendants Medical Research Institute (FAMRI)
First prize, Resident Research Competition, Missouri Chapter, American College of Surgeons, 1997
Samuel A. Wells Resident Research Award, Washington University School of Medicine, 1999
Inducted into Alpha Omega Alpha, 1999
Curci JA, Fillinger MF, Naslund TC, Rubin BG; for the Excluder Bifurcated Endoprosthesis Investigators. Clinical trial results of a modified gore excluder endograft: comparison with open repair and original device design. Annals of Vascular Surgery. 2007;21(3):328-38. Epub 2007 Mar 7.
Bergoeing MP, Arif B, Hackmann AE, Ennis TL, Thompson RW, Curci JA. Cigarette smoking increases aortic dilatation without affecting matrix metalloproteinase-9 and -12 expression in a modified mouse model of aneurysm formation. Journal of Vascular Surgery. 2007;45(6):1217-1227. Epub 2007 Mar 29.
Thompson RW, Curci JA, Ennis TL, Mao D, Pagano MB, Pham CT. Pathophysiology of abdominal aortic aneurysms: insights from the elastase-induced model in mice with different genetic backgrounds. Annals of the New York Academy of Sciences. 2006;1085:59-73.
Bergoeing MP, Thompson RW, Curci JA. Pharmacological targets in the treatment of abdominal aortic aneurysms. Expert Opin Ther Targets. 2006;10(4):547-559.
Chambers CM, Curci JA. Treatment of nonaortic aneurysms in the endograft era: aneurysms of the innominate and subclavian arteries. Semin Vasc Surg. 2005;18(4):184-190.
Buckley C, Wyble CW, Borhani M, Ennis TL, Kobayashi DK, Curci JA, Shapiro SD, Thompson RW. Accelerated enlargement of experimental abdominal aortic aneurysms in a mouse model of chronic cigarette smoke exposure. Journal of American College of Surgeons. 2004;199(6):896-903.
Curci JA, Thompson RW. Adaptive cellular immunity in aortic aneurysms: cause, consequence, or context? Journal of Clinical Investigation. 2004;114(2):168-171.
Curci JA, Sanchez LA. Medical treatment of peripheral arterial disease. Current Opinion in Cardiology. 2003;18(6):425-430.
Liao S, Curci JA, Kelley BJ, Sicard GA, Thompson RW. Accelerated replicative senescence of medial smooth muscle cells derived from abdominal aortic aneurysms compared to the adjacent inferior mesenteric artery. Journal of Surgical Research. 2000;92(1):85-95.
Liao S, Miralles M, Kelley BJ, Curci JA, Borhani M, Thompson RW. Suppression of experimental abdominal aortic aneurysms in the rat by treatment with angiotensin converting enzyme inhibitors. Journal of Vascular Surgery. 2001;33(5):1057-1064.
Pyo R, Lee JK, Shipley JM, Curci JA, Mao D, Ziporin SJ, Ennis TL, Shapiro SD, Senior RM, Thompson RW. Targeted gene disruption of matrix metalloproteinase-9 (gelatinase B) suppresses development of experimental abdominal aortic aneurysms. Journal of Clinical Investigation. 2000;105(11):1641-1649.
Curci JA, Mao D, Bonner D, Allen BT, Rubin BG, Reilly JM, Sicard GA, Thompson RW. Preoperative treatment with doxycycline reduces aortic wall expression and activation of matrix metalloproteinases in patients with abdominal aortic aneurysms. Journal of Vascular Surgery. 2000;31(2):325-342.
Moore G, Liao S, Curci JA, Starcher BC, Martin RL, Hendricks RT, Chen JJ, Thompson RW. Suppression of experimental abdominal aortic aneurysms by systemic treatment with a hydroxamate-based matrix metalloproteinase inhibitor (RS 132908). Journal of Vascular Surgery. 1999;29(3):522-532.
Curci JA, Petrinec D, Liao S, Golub LM, Thompson RW. Pharmacologic suppression of experimental abdominal aortic aneurysms: a comparison of doxycycline and four chemically modified tetracyclines. Journal of Vascular Surgery. 1998;28(6):1082-1093.
Curci JA, Liao S, Huffman MD, Shapiro SD, Thompson RW. Expression and localization of macrophage elastase (matrix metalloproteinase-12) in abdominal aortic aneurysms. Journal of Clinical Investigation. 1998;102(11):1900-1910.
Pub Med page for John A. Curci, M.D., F.A.C.S.
Washington University School of Medicine
Department of Surgery
Section of Vascular Surgery
Campus Box 8109
St. Louis, MO 63110
(314) 362-7406
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